Question 1:
Can you list 10 recombinant proteins which are used in medical practice? Find out where they are used as therapeutics (use the internet).
ANSWER:
Recombinant proteins are obtained from the recombinant DNA technology. This technology involves the transfer of specific genes from an organism into another organism using vectors and restriction enzymes as molecular tools.
Ten recombinant proteins used in medical practice are −
Recombinant protein |
Therapeutic use |
|
1. |
Insulin |
Treatment for type I diabetes mellitus |
2. |
Interferon-α |
Used for chronic hepatitis C |
3. |
Interferon -β |
Used against herpes and viral enteritis |
4. |
Coagulation factor VIII |
Treatment of haemophilia A |
5. |
Coagulation factor IX |
Treatment of haemophilia B |
6. |
DNAase I |
Treatment of cystic fibrosis |
7. |
Anti-thrombin III |
Prevention of blood clot |
8. |
Interferon B |
For treatment of multiple sclerosis |
9. |
Human recombinant growth hormone |
For promoting growth in an individual |
10. |
Tissue plasminogen activator |
Treatment of acute myocardial infarction |