At which stage of cell cycle colchicine arrests the spindle?
a)	Anaphase	b)	Prophase	c)	Telophase	d)	Interphase

(a)

Colchicine is an antimitotic drug (alkaloid) which is obtained from Colchicum (family-Lilliaceae). It binds to one tubulin molecule and prevents its polymerization. The depolymerisation of tubulin results in disappearance of mitotic spindle, blocking the cells mitotic chromosomal division of metaphase and anaphase