SaraNextGen.Com

Functioning of kidney is efficiently regulated by

a)

ANF

b)

JGA

c)

Both (a) and (b)

d)

Lungs



Question ID - 3688 | SaraNextGen Top Answer

Functioning of kidney is efficiently regulated by

a)

ANF

b)

JGA

c)

Both (a) and (b)

d)

Lungs

1 Answer
127 votes
Answer Key / Explanation : (c) -

(c)

The JGA plays a complex regulatory role. A fall in glomerular blood flow/glomerular blood pressure/GFR can activate the JG cells to release renin, which converts angiotensin ogen in blood to angiotensin I and further to angiotensin-II. Angiotensin-II, being a powerful vasoconstrictor, increase the glomerular blood pressure and thereby GFR. Angiotensin-II also activates the adrenal cortex to release aldosterone. Aldosterone causes reabsorption of  and water from the distal parts of the tubule. This also leads to an increase in blood pressure and GFR. This complex mechanism is generally known as the renin-angiotensin mechanism.

An increase in blood flow to the atria of the heart can cause the release of Atrial Natriuretic Factor (ANF). ANF can cause vasodilation (dilation of blood vessels) and thereby decrease the blood pressure. ANF mechanism, therefore, acts as a check on the renin-angiotensin mechanism

127 votes


127