Which of the following statements are true/false? The blood transports carbon dioxide comparatively easily because of its highest solubility. Approximately 8.9% of carbon dioxide is transported being dissolved in the plasma of blood. The carbon dioxide produced by the tissues, diffuses passively into the blood stream and passes into red blood corpuscles and react with water to form. The oxyhaemoglobin of the erythrocytes is basic. The chloride ions diffuse from plasma into the erythrocytes to maintain ionic balance.
a)	I, III and V are true , II and IV are false	b)	I, III and V are false, II and IV are true
c)	I, II and IV are true, III and V are false	d)	I, II and IV are false, III and V are true

(a)

 transport in blood : Transport of  by blood is must easier/simple than that of  due to high solubility of  in water.

Most of the  70% of  is transported as bicarbonate  in blood. 23% as carbaminohaemoglobin  and 7% of  is dissolved in the plasma.

 produced by the tissues, diffuses passively into the blood plasma and reacts with water forming carbonic acid. The reaction occurs very rapidly inside RBCs because of the presence of enzyme carbonic anhydrase.

Chloride shift : To maintain electro-chemical neutrality of plasma many chloride ions diffuse from plasma into RBCs and bicarbonates pass out. The chloride content of RBCs increases when oxygenated blood becomes deoxygenated. This is termed as chloride shift or Hamburger shift.

Haldane’s effect : Oxygenated blood behaves as strong acid.  More and more oxyhaemoglobin is formed in lungs, which releases  increasing the acidity of blood. This  combines with bicarbonate forming carbonic acid and soon dissociates.